Interferon alpha for chronic hepatitis D
نویسندگان
چکیده
منابع مشابه
EFFICACY AND SAFETY OF COMBINATION THERAPY OF INTERFERON-ALPHA 2B PLUS RIBAVIRIN FOR CHRONIC HEPATITIS C
Introduction: The aim of this study is to assess the therapeutic efficacy and safety of a particular brand of IFN alpha (PDferon B®) in combination with ribavirin (RlBA) on Iranian patients with chronic hepatitis C (CHC). The addition of RIBA to the standard treatment with interferon (IFN) alpha led to an improvement in sustained virologic response (SVR) from less than 20% with IFN monother...
متن کاملAlpha interferon and ribavirin combination therapy of chronic hepatitis D.
The success of alpha interferon (IFN-alpha) monotherapy for the treatment of chronic hepatitis D is very limited. In this study, the efficacy of IFN-alpha and ribavirin combination therapy for chronic hepatitis D was investigated. Nineteen patients (15 males; mean age +/- standard deviation, 36.8 +/- 12.8 years) with chronic hepatitis D who were treated with IFN-alpha2b (10 million U, three tim...
متن کاملRetreatment with interferon-alpha and ribavirin in primary interferon-alpha non-responders with chronic hepatitis C.
BACKGROUND/AIMS Combination therapy with interferon-alpha (IFN-alpha) plus ribavirin is more efficacious than IFN-alpha monotherapy in previously untreated patients with chronic hepatitis C and patients with IFN-alpha relapse. Only limited data are available in IFN-alpha non-responders. In a multicenter trial we therefore evaluated the efficacy of combination therapy in IFN-alpha-resistant chro...
متن کاملinterferon alpha-2b therapy in chronic hepatitis delta
results overall, 3 (15%) subjects achieved svr, 10 cases (50%) relapsed after treatment cessation and 7 (35%) patients did not clear hdv during the treatment. conclusions hdv coinfection with hbv had very low response rate to high doses and long durations of ifn α-2b therapy. objectives we aimed to determine the efficacy of ifn α-2b therapy in patients with hbv/hdv coinfection. patients and met...
متن کاملInterferon Alpha-2b Therapy in Chronic Hepatitis Delta
BACKGROUND Approximately 5% of hepatitis B virus (HBV) carriers are coinfected with hepatitis D virus (HDV). HBV/HDV coinfection is a major cause of cirrhosis and end stage liver disease in chronic HBsAg carriers. The only approved therapy for chronic hepatitis delta is interferon alpha (IFN α) in either pegylated or conventional forms. Although higher doses and longer durations of IFN α therap...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2011
ISSN: 1465-1858
DOI: 10.1002/14651858.cd006002.pub2